Italian Greyhounds: Bred for Bad Teeth

Scientists at UC Davis have identified the gene responsible for tooth disorder common in Italian greyhounds (IG). Enamel hypoplasia in IGs is characterized by discolored, rough surfaced teeth, the condition is caused by incomplete mineral deposition and/or defective organization of enamel during the development of the tooth. The genetic disorder was traced back to a 5bp…

Angelina Jolie, Evolution and Pleiotropy

Angelina Jolie recently revealed she underwent a double mastectomy; a prophylactic measure to combat the risk of breast cancer associated with BRCA1 gene she carries. Like many other ‘disease’ genes BRCA1 and BRCA2 show evidence of positive selection, suggesting a fitness advantage. To understand how BRCA provides an evolutionary advantage we have to look at the other…